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Table 1 List of gene perturbations that affect survival of larval abdominal muscles in metamorphosis

From: Live imaging of muscle histolysis in Drosophila metamorphosis

Gene/synonym

gene pertur-bation

Stock ID/TRiP #

Muscle phenotype

Flightless

Chromator (Chro), control

RNAi

B-36084/GL00503

wildtype

no

Rm62

RNAi

B-34829/HMS00144

DIOM cell death

yes

Cysteine Proteinase 1 (Cp1)/Cathepsin L

RNAi

B-32932/HMS00725

DIOM cell death

no

Cysteine Proteinase 1 (Cp1)/Cathepsin L

RNAi

B-41939/HMS02336

DIOM cell death

no

TOR/TOR-TED

DN

B-7013

DIOM cell death, delay of DEOM cell death

partial

AMP-activated protein kinase α (AMPKα)/SNF1a

RNAi

B-35137/GL00004

DIOM loss of morphology and degeneration

yes

Atrophin (Atro)/Grunge

RNAi

B-32961/HMS00756

Inhibition of DEOM cell death

yes

  1. Initial phenotypic assessment of a minimum of 20 pupae per genotype was carried out using a macro zoom microscope