Fig. 7From: Apontic regulates somatic stem cell numbers in Drosophila testesApt functions as a feedback inhibitor of the JAK/STAT pathway in CySCs. Apontic (Apt) is required in the CySCs as a feedback inhibitor of STAT signaling to promote the CySC to cyst cell transition: see text for details. Apt’s genetic interactions with the STAT-targeting miR-279 and the conserved inhibitor of STAT, Socs36E, suggest it may mediate expression of these targets, as in ovaries. GSC=Germline Stem Cell, CySC=Cyst Stem CellBack to article page