Potential role in blastema | Abbreviation | Gene name | Reference |
---|---|---|---|
Regulation of tissue differentiation | CAPSL | Calcyphosine-like | [77] |
 | CRABP1 | Cellular retinoic acid binding protein 1 | [78] |
Skeletal differentation and development | ACAN | Aggrecan | [79] |
 | COL9A2 | Collagen, type IX, alpha 2 | [80] |
 | DACT1 | Dishevelled-Binding Antagonist Of Beta-Catenin 1 | [42] |
 | EMILIN3 | Elastin Microfibril Interfacer 3 | [52] |
 | FGFR3 | Fibroblast growth factor receptor 3 | [40] |
 | FOXC1 | Forkhead Box C1 | [81] |
 | GDF5 | Growth differentiation factor 5 | [82] |
 | ITGBL1 | Integrin, beta-like 1 (with EGF-like) | [83] |
 | LECT1 | Leukocyte cell derived chemotaxin 1 | [84] |
 | TGFBR2 | Transforming Growth Factor, Beta Receptor II | [85] |
Muscle and tendon differentation | MYF5 | Myogenic factor 5 | [86] |
 | OLFM2 | Neuronal Olfactomedin Related ER Localized Protein 2 | [87] |
 | PLAC9 | Placenta-specific 9 | [88] |
Axonal guidance and neural function | ACCN1 | Acid-sensing ion channel 2 | [89] |
 | CDH20 | Cadherin 20, Type 2 | [90] |
 | CPA6 | Carboxypeptidase A6 | [91] |
 | DAO | D-Amino-Acid Oxidase | [92] |
 | EPHA5 | Ephrin type-A receptor 5 | [93] |
 | ERMN | Ermin, ERM-Like Protein | [94] |
 | FAM19A5 | Family With Sequence Similarity 19 (Chemokine (C-C Motif)-Like) Member 5 | [95] |
 | FABP7 | Fatty acid binding protein 7, brain | [96] |
 | GPR37L1 | G Protein-Coupled Receptor 37 Like 1 | [97] |
 | LPHN3 | Latrophilin 3 | [98] |
 | NRCAM | Neuronal cell adhesion molecule | [99] |
 | OTOS | Otospiralin | [100] |
 | PARK7 | Parkinson protein 7 | [101] |
 | RGMA | Repulsive Guidance Molecule Family Member A | [102] |
 | RGMB | RGM domain family, member B | [103] |
 | SLC7A10 | Solute Carrier Family 7 (Neutral Amino Acid Transporter Light Chain, Asc System), Member 10 | [104] |
 | TMEM47 | Transmembrane Protein 47 | [105] |
Angiogenesis | ANGPTL1 | Angiopoietin-related protein 1 | [106] |
 | C1QTNF6 | C1q and tumor necrosis factor related protein 6 | [107] |
 | OSR1 | Odd-skipped related 1 | [108] |
Regulation of tissue growth | CDKL1 | Cyclin-dependent kinase-like 1 | [109] |
 | CDKN2C | Cyclin-Dependent Kinase Inhibitor 2C | [110] |
 | LRIG3 | Leucine-Rich Repeats And Immunoglobulin-Like Domains 3 | [111] |
 | PDGFRL | Platelet-Derived Growth Factor Receptor-Like | [112] |
 | PTPRD | Protein tyrosine phosphatase, receptor type, D | [113] |
 | TMEM22 | Solute carrier family 35 member G2 | [114] |
Genes with higher expression in EB and apical-LB tissues | Â | Â | Â |
Cell Signaling | ESRRG | Estrogen-related receptor gamma | [115] |
 | FAM150A | Family With Sequence Similarity 150, Member A | [116] |
 | FGF8 | Fibroblast Growth Factor 8 | [117] |
 | G3BP2 | Ras GTPase-activating protein-binding protein 2 | [22] |
DNA Repair and Modification | HABP4 | Intracellular hyaluronan-binding protein 4 | [118] |
 | JARID2 | Jumonji, AT Rich Interactive Domain 2 | [62] |
 | OBFC2A | NABP1 nucleic acid binding protein 1 | [119] |
 | ZMYM2 | Zinc Finger, MYM-Type 2 | [120] |
Ubiquination | ASB6 | Ankyrin repeat and SOCS box protein 6 | [121] |
 | SENP1 | SUMO1/sentrin specific peptidase 1 | [122] |
 | SPSB4 | SplA/Ryanodine Receptor Domain And SOCS Box Containing 4 | [123] |
 | UBA3 | Ubiquitin-like modifier activating enzyme 3 | [124] |
Transcriptional Regulation and RNA processing | HBP1 | HMG-Box Transcription Factor 1 | [125] |
 | NR2C1 | Nuclear receptor subfamily 2, group C, member 1 | [126] |
 | SFRS2 | Serine/Arginine-Rich Splicing Factor 2 | [127] |
 | SNRPA1 | Small Nuclear Ribonucleoprotein Polypeptide A | [128] |
 | ZNF674 | Zinc Finger Protein 674 | [129] |
Translation | ETF1 | Eukaryotic Translation Termination Factor | [130] |
 | ISG20L2 | Interferon stimulated exonuclease gene 20 kDa-like 2 | [131] |
 | PUS3 | Pseudouridylate Synthase 3 | [132] |
Mitochondrial Function | C21orf2 | Chromosome 21 Open Reading Frame 2 | [133] |
 | DNM1L | Dynamin-1-like protein | [134] |
 | TBC1D20 | TBC1 Domain Family, Member 20 | [135] |
 | WARS2 | Tryptophanyl TRNA Synthetase 2, Mitochondrial | [136] |
 | YARS2 | Tyrosyl-tRNA synthetase 2, mitochondrial | [137] |
Nerve Related | MAPK6 | Mitogen-Activated Protein Kinase 6 | [138] |
 | MLLT11 | Myeloid/Lymphoid Or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila); Translocated To, 11 | [139] |
 | RTN4 | Reticulon 4 | [140] |
 | SMN1 | Survival of motor neuron 1, telomeric | [141] |