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Table 1 Genes with higher expression in basal-LB tissues

From: Positional plasticity in regenerating Amybstoma mexicanum limbs is associated with cell proliferation and pathways of cellular differentiation

Potential role in blastema

Abbreviation

Gene name

Reference

Regulation of tissue differentiation

CAPSL

Calcyphosine-like

[77]

 

CRABP1

Cellular retinoic acid binding protein 1

[78]

Skeletal differentation and development

ACAN

Aggrecan

[79]

 

COL9A2

Collagen, type IX, alpha 2

[80]

 

DACT1

Dishevelled-Binding Antagonist Of Beta-Catenin 1

[42]

 

EMILIN3

Elastin Microfibril Interfacer 3

[52]

 

FGFR3

Fibroblast growth factor receptor 3

[40]

 

FOXC1

Forkhead Box C1

[81]

 

GDF5

Growth differentiation factor 5

[82]

 

ITGBL1

Integrin, beta-like 1 (with EGF-like)

[83]

 

LECT1

Leukocyte cell derived chemotaxin 1

[84]

 

TGFBR2

Transforming Growth Factor, Beta Receptor II

[85]

Muscle and tendon differentation

MYF5

Myogenic factor 5

[86]

 

OLFM2

Neuronal Olfactomedin Related ER Localized Protein 2

[87]

 

PLAC9

Placenta-specific 9

[88]

Axonal guidance and neural function

ACCN1

Acid-sensing ion channel 2

[89]

 

CDH20

Cadherin 20, Type 2

[90]

 

CPA6

Carboxypeptidase A6

[91]

 

DAO

D-Amino-Acid Oxidase

[92]

 

EPHA5

Ephrin type-A receptor 5

[93]

 

ERMN

Ermin, ERM-Like Protein

[94]

 

FAM19A5

Family With Sequence Similarity 19 (Chemokine (C-C Motif)-Like) Member 5

[95]

 

FABP7

Fatty acid binding protein 7, brain

[96]

 

GPR37L1

G Protein-Coupled Receptor 37 Like 1

[97]

 

LPHN3

Latrophilin 3

[98]

 

NRCAM

Neuronal cell adhesion molecule

[99]

 

OTOS

Otospiralin

[100]

 

PARK7

Parkinson protein 7

[101]

 

RGMA

Repulsive Guidance Molecule Family Member A

[102]

 

RGMB

RGM domain family, member B

[103]

 

SLC7A10

Solute Carrier Family 7 (Neutral Amino Acid Transporter Light Chain, Asc System), Member 10

[104]

 

TMEM47

Transmembrane Protein 47

[105]

Angiogenesis

ANGPTL1

Angiopoietin-related protein 1

[106]

 

C1QTNF6

C1q and tumor necrosis factor related protein 6

[107]

 

OSR1

Odd-skipped related 1

[108]

Regulation of tissue growth

CDKL1

Cyclin-dependent kinase-like 1

[109]

 

CDKN2C

Cyclin-Dependent Kinase Inhibitor 2C

[110]

 

LRIG3

Leucine-Rich Repeats And Immunoglobulin-Like Domains 3

[111]

 

PDGFRL

Platelet-Derived Growth Factor Receptor-Like

[112]

 

PTPRD

Protein tyrosine phosphatase, receptor type, D

[113]

 

TMEM22

Solute carrier family 35 member G2

[114]

Genes with higher expression in EB and apical-LB tissues

   

Cell Signaling

ESRRG

Estrogen-related receptor gamma

[115]

 

FAM150A

Family With Sequence Similarity 150, Member A

[116]

 

FGF8

Fibroblast Growth Factor 8

[117]

 

G3BP2

Ras GTPase-activating protein-binding protein 2

[22]

DNA Repair and Modification

HABP4

Intracellular hyaluronan-binding protein 4

[118]

 

JARID2

Jumonji, AT Rich Interactive Domain 2

[62]

 

OBFC2A

NABP1 nucleic acid binding protein 1

[119]

 

ZMYM2

Zinc Finger, MYM-Type 2

[120]

Ubiquination

ASB6

Ankyrin repeat and SOCS box protein 6

[121]

 

SENP1

SUMO1/sentrin specific peptidase 1

[122]

 

SPSB4

SplA/Ryanodine Receptor Domain And SOCS Box Containing 4

[123]

 

UBA3

Ubiquitin-like modifier activating enzyme 3

[124]

Transcriptional Regulation and RNA processing

HBP1

HMG-Box Transcription Factor 1

[125]

 

NR2C1

Nuclear receptor subfamily 2, group C, member 1

[126]

 

SFRS2

Serine/Arginine-Rich Splicing Factor 2

[127]

 

SNRPA1

Small Nuclear Ribonucleoprotein Polypeptide A

[128]

 

ZNF674

Zinc Finger Protein 674

[129]

Translation

ETF1

Eukaryotic Translation Termination Factor

[130]

 

ISG20L2

Interferon stimulated exonuclease gene 20 kDa-like 2

[131]

 

PUS3

Pseudouridylate Synthase 3

[132]

Mitochondrial Function

C21orf2

Chromosome 21 Open Reading Frame 2

[133]

 

DNM1L

Dynamin-1-like protein

[134]

 

TBC1D20

TBC1 Domain Family, Member 20

[135]

 

WARS2

Tryptophanyl TRNA Synthetase 2, Mitochondrial

[136]

 

YARS2

Tyrosyl-tRNA synthetase 2, mitochondrial

[137]

Nerve Related

MAPK6

Mitogen-Activated Protein Kinase 6

[138]

 

MLLT11

Myeloid/Lymphoid Or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila); Translocated To, 11

[139]

 

RTN4

Reticulon 4

[140]

 

SMN1

Survival of motor neuron 1, telomeric

[141]