TY - JOUR AU - Hoppe, Beate AU - Pietsch, Stefan AU - Franke, Martin AU - Engel, Sven AU - Groth, Marco AU - Platzer, Matthias AU - Englert, Christoph PY - 2015 DA - 2015/11/17 TI - MiR-21 is required for efficient kidney regeneration in fish JO - BMC Developmental Biology SP - 43 VL - 15 IS - 1 AB - Acute kidney injury in mammals, which is caused by cardiovascular diseases or the administration of antibiotics with nephrotoxic side-effects is a life-threatening disease, since loss of nephrons is irreversible in mammals. In contrast, fish are able to generate new nephrons even in adulthood and thus provide a good model to study renal tubular regeneration. SN - 1471-213X UR - https://doi.org/10.1186/s12861-015-0089-2 DO - 10.1186/s12861-015-0089-2 ID - Hoppe2015 ER -