Skip to main content
Fig. 3 | BMC Developmental Biology

Fig. 3

From: Cooperative and independent functions of FGF and Wnt signaling during early inner ear development

Fig. 3

Expression patterns of genes encoding Wnt ligands and receptors are unchanged in Spry1 −/− ; Spry2 −/− embryos. aj In situ hybridization analyses of genes encoding Wnt ligands and receptors in Spry1 −/− ; Spry2 −/− embryos and controls at OEPD or early otic placode stages. Lateral views of whole-mount embryos are shown; embryos are oriented as indicated. Pre-otic regions are bracketed. k Semi-quantitative reverse-transcriptase PCR analyses of candidate Wnt and Fzd transcript levels in RNA collected from 5 – 7 s hindbrain and OEPD-containing tissue microdissected from the genotypes indicated. Wnt genes (Wnt1, Wnt3a, Wnt6, and Wnt8a) with known expression adjacent to the OEPD are controls. Scale bar, 100 μm

Back to article page