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Table 1 Strain dependent viability of euploid Tbx5 +/− mice at weaning

From: The pattern of congenital heart defects arising from reduced Tbx5 expression is altered in a Down syndrome mouse model

Genetic background

Frequency of Tbx5 +/− genotype

C57BL/6J

11 % (n = 591)

B6;C3H (75 % B6, 25 % C3H)

21 % (n = 131)

129SvEv/129SvJ

10 %a

Black Swiss/SvJ

28 %a

  1. a[20]