From: The pattern of congenital heart defects arising from reduced Tbx5 expression is altered in a Down syndrome mouse model
Genetic background
Frequency of Tbx5 +/− genotype
C57BL/6J
11 % (n = 591)
B6;C3H (75Â % B6, 25Â % C3H)
21 % (n = 131)
129SvEv/129SvJ
10 %a
Black Swiss/SvJ
28 %a