Skip to main content
Fig. 4 | BMC Developmental Biology

Fig. 4

From: The pattern of congenital heart defects arising from reduced Tbx5 expression is altered in a Down syndrome mouse model

Fig. 4

Pitx2 expression in E13.5 WT and trisomic, Tbx5 +/− embryos. In situ hybridization of coronal sections of wild type (a,b) and Ts65Dn;Tbx5 +/− (c,d) mice. Pitx2 expression can be seen in the left atrium of the WT animals (a). Pitx2 expression is much weaker in the trisomic, Tbx5 +/− mutants (c). Scale bar equals to 100 μm. RA/LA: right/left atrium. In situ hybridization results were verified through quantitative PCR in E13.5 hearts (e). Error bars are standard deviation from the mean

Back to article page

BMC Developmental Biology

ISSN: 1471-213X

Contact us