Fig. 5
From: The Aurora A-HP1γ pathway regulates gene expression and mitosis in cells from the sperm lineage
Rescue of mitosis and meiosis processes mediated by HP1γ is dependent on its phosphorylation status. a-c. Gene Ontology (GO) ANOVA analysis of rescued targets was performed and revealed significant (p < 0.05) enrichment of mitosis and meiosis associated processes, as well as processes involved in cellular expansion and differentiation for (a) HP1γ, (b) HP1γ and HP1γ-S83A but not HP1γ-S83D or (c) HP1γ and HP1γ-S83D but not HP1γ-S83A. Targets, rescued by the wild type protein but not one of the mutants, indicate targets explicitly dependent on HP1γ phosphorylation or dephosphorylation