Figure 3

Mean pharynx and body length measurements ± standard deviation of sma-3(e491) (A, B) and sma-3(wk30) (C, D) animals from various sma-3 minigene rescue experiments at 96 hrs AEL. Wild type (Wt) N2 is included for comparison. Vertical labels indicate tissue specific promoter-sma-3 minigene fusion rescue constructs in each strain, except for elt-3p::gfp::sma-3 which indicates the elt-3p::gfp::sma-3 transgene (pCS223) was used. In each case, we measured animals carrying the transgenic array (+) and siblings that lacked the array (−), as indicated by presence of the transformation marker (either elt-2p::tdTomato::His2B or myo-3p::wCherry). For each transgene tested, a representative line is shown; complete data for multiple lines is provided in Additional file 5. All transgenic animal means (+) were statistically significantly different from non-transgenic sibling means (−) (p < 0.001) unless otherwise indicated. ** denotes a significant difference of p < 0.001.