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Figure 3 | BMC Developmental Biology

Figure 3

From: Mechanistic target of rapamycin complex 1 signaling regulates cell proliferation, cell survival, and differentiation in regenerating zebrafish fins

Figure 3

Rapamycin treatment inhibits fin regeneration until 72 hpa. (A) Scheme of rapamycin treatment from – 12 h to 72 hpa. (B, C) Rapamycin treatment significantly inhibited fin regeneration from – 12 h to 72 hpa (pre-blastema formation, blastema formation, and regenerative outgrowth stages), when compared to DMSO treatment. Dashed lines indicate the amputation planes. ** p < 0.01 by Student’s t-test. Error bars represent the standard error of 4 independent experiments. Scale bars: 500 μm in B.

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