Figure 4
From: Ras promotes cell survival by antagonizing both JNK and Hid signals in the Drosophilaeye
Genetic interactions of ras with genes involved in growth and survival. (A) rasKPmutant eye is small and rough. (B) GMR-p35 only partly suppresses the rasKP-induced cell death. (C) In the hid null background, rasKP-induced cell death is also partially suppressed. Ectopic expression of PI3K (D), Akt (E) and buffy (F) have no effect on the rasKPeye phenotype. Genotypes: (A)GMR-Gal4/CyO; rasKP/rasKP, (B)GMR-p35/CyO; rasKP/rasKP, (C)Df(3L)H99, rasKP/hid05014rasKP, (D)GMR-Gal4/UAS-p110; rasKP/rasKP, (E)GMR-Gal4/UAS-AKT; rasKP/rasKP, (F)GMR-Gal4/UAS-buffy; rasKP/rasKP.