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Figure 1 | BMC Developmental Biology

Figure 1

From: Hedgehog pathway responsiveness correlates with the presence of primary cilia on prostate stromal cells

Figure 1

Stromal and epithelial cells of the newborn prostate feature primary cilia. Tissue sections of the P1 UGS were costained with DAPI (A), P63, a marker of basal epithelial cells (B), and anti-acetylated tubulin (C). The merged image (D) illustrates that both stromal cells, outside of the ordered ring of basal epithelium cells (arrows), as well as epithelial cells within the basal layer (arrow heads) feature primary cilia. (E) Whole mount in situ hybridization for Notch1 of the P1 UGS. Blue staining shows Notch1-expressing epithelium (BN, bladder neck; PU, prostatic urethra; SV seminal vesicle). Areas of anterior (AP) and dorsal (DP) prostate budding are indicated. (F) Scanning electron micrograph of the P1 male UGS. (G) High magnification image of the boxed area in F showing cilia on the surface mesenchyme (arrows).

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