Figure 7
CAP-G-mcherry is mislocalized during gastrula stage mitoses upon loss of its interaction partners CAP-H and CAP-D2 and localizes to the cytoplasm. (A, B) The different mitotic stages are recognizable by transgenic H2A::GFP expression. M, metaphase; PM, prometaphase; T, telophase. (C, D) Occurrence of chromatid bridges in MOcap-h+cap-d2 injected embryos. Red arrow indicates a chromatid bridge in between two anaphase nuclei. Red arrowhead marks aberrant genetic material associated with a decondensed nucleus.