Figure 5
Expression of the creatine synthesizing enzymes AGAT and GAMT in the brain during fetal and neonatal development. A, Brain AGAT mRNA expression; B. Brain GAMT mRNA expression. All mRNA data are normalized to 18S and shown relative to 37 days gestation. AGAT and GAMT protein could not be detected with western blot, possibly due to low level expression in whole brain homogenates. Data points not sharing the same symbol indicate expression is significantly different to all others (p < .05). Mean ± SE. GA, gestational days; PN, postnatal days.