Figure 1
From: The pluripotency factor LIN28 marks undifferentiated spermatogonia in mouse
Expression of LIN28 in mouse testis. Western blot analysis was performed on 20 μg of protein extracts for each sample. β-actin served as a control. Molecular weight standards were marked in kDa. (A) Western blot analysis of LIN28 in adult mouse tissues. (B) Absence of LIN28 in germ cell-deficient XXY* testes. Testes were collected from adult and post-natal day 10-old mice. V6.5 mouse embryonic stem (ES) cells served as a positive control. LIN28 was absent in fibroblast feeder cells. (C) Developmental expression of LIN28 in postnatal testes. Testes were collected from mice of postnatal day 1 through adulthood.