From: Foxl2functions in sex determination and histogenesis throughout mouse ovary development
 | Foxl2null-depleted | Foxl2null-enriched |  | ||
---|---|---|---|---|---|
Pathway | N | Proportion | N | Proportion | p-value |
   Ubiquitin mediated proteolysis | (42) | (0,06) | 11 | 0,02 | 0,00003 |
   Insulin signaling pathway | (35) | (0,05) | 8 | 0,01 | 0,00004 |
   ErbB signaling pathway | (28) | (0,04) | 6 | 0,01 | 0,00018 |
   MAPK signaling pathway | (58) | (0,09) | 26 | 0,04 | 0,00067 |
   Axon guidance | (40) | (0,06) | 15 | 0,02 | 0,00132 |
   Prostate cancer | (22) | (0,03) | 5 | 0,01 | 0,00146 |
   Colorectal cancer | (27) | (0,04) | 8 | 0,01 | 0,00179 |
   Long-term potentiation | (19) | (0,03) | 4 | 0,01 | 0,00252 |
   Adherens junction | (24) | (0,04) | 7 | 0,01 | 0,0032 |
   Glioma | (19) | (0,03) | 5 | 0,01 | 0,00644 |
   Apoptosis | (15) | (0,02) | 3 | 0,00 | 0,0074 |
   Wnt signaling pathway | (41) | (0,06) | 19 | 0,03 | 0,00773 |
   Alanine and aspartate metabolism | 0 | 0,00 | (8) | (0,01) | 0,00318 |
   One carbon pool by folate | 2 | 0,00 | (13) | (0,02) | 0,00333 |
   Glyoxylate and dicarboxylate metabolism | 0 | 0,00 | (9) | (0,01) | 0,00154 |
   Glycolysis/Gluconeogenesis | 3 | 0,00 | (19) | (0,03) | 0,00035 |
   Oxidative phosphorylation | 7 | 0,01 | (33) | (0,05) | 0,00001 |
   Ribosome (protein synthesis) | 3 | 0,00 | (79) | (0,13) | 0 |
 | Wnt4 null-depleted | Wnt4 null-enriched |  | ||
Pathway | N | Proportion | N | Proportion | p-value |
   Ribosome (protein synthesis) | (55) | (0,09) | 7 | 0,01 | 0 |
   Oxidative phosphorylation | (51) | (0,08) | 7 | 0,01 | 0 |
   Glycolysis/Gluconeogenesis | (18) | (0,03) | 3 | 0,00 | 0,00008 |
   Fructose and mannose metabolism | (15) | (0,02) | 4 | 0,01 | 0,00194 |
   Calcium signaling pathway | 16 | 0,03 | (45) | (0,06) | 0,00548 |
   Neuroactive ligand-receptor interaction | 19 | 0,03 | (52) | (0,07) | 0,00441 |
   Leukocyte transendothelial migration | 9 | 0,01 | (33) | (0,04) | 0,00396 |
   Cell adhesion molecules (CAMs) | 7 | 0,01 | (31) | (0,04) | 0,00141 |
   Cytokine-cytokine receptor interaction | 18 | 0,03 | (54) | (0,07) | 0,00135 |
   Natural killer cell mediated cytotoxicity | 9 | 0,01 | (36) | (0,05) | 0,00115 |
   Complement and coagulation cascades | 2 | 0,00 | (19) | (0,02) | 0,00131 |
   ECM-receptor interaction | 9 | 0,01 | (37) | (0,05) | 0,00076 |
   Focal adhesion | 23 | 0,04 | (70) | (0,09) | 0,00014 |