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Figure 4 | BMC Developmental Biology

Figure 4

From: The DEAD-box protein MEL-46 is required in the germ line of the nematode Caenorhabditis elegans

Figure 4

The mel-46 gene and protein structure. (A) mel-46 mRNA. The 10 exons are represented by boxes with lines (introns) joining them. The mel-46 mRNA is trans-spliced to the spliced leader SL1. The asterisk designates mutation yt5 (C → T) that leads to a premature stop codon at position 2719. The deletion allele tm1739 removes 425 bp of the genomic sequence. The coding regions for the DEAD box and the predicted helicase domain are shown in shaded and gray, respectively. (B) MEL-46 protein. The mutation yt5 creates a truncated protein. The DEAD box (shaded box), the helicase domain (grey box) and the 16 amino acid oligo-peptide that was used to raise antibodies (black box) are indicated.

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