Figure 8

Comparative in vitro gene expression between E14 + 7 SMG explants with NFκB loss-of-function and those with Eda gain-of-function. A. Quantitative RT-PCR derived relative gene expression in SN50-treated (+SN50) and Eda-treated (+Eda) explants compared to controls. B. Probabilistic Neural Network (PNN) analysis was used to determine the contribution of each gene to the discrimination between SN50-treated and Eda-treated phenotypes. PNN analyses identify the relative importance (0–1, with 0 being of no relative importance and 1 being relatively most important) of specific gene expression changes that distinguish between SN50-treated and Eda-treated phenotypes.