Figure 4

Tabby SMGs exhibit a marked increase in Egf, Tgfα and Egfr protein expression. A, B. Immunolocalization of Egf protein in E18 WT (A) and Tabby (B) SMGs. C, D. Immunolocalization of Tgfα protein in E18 WT (C) and Tabby (D) SMGs. E, F. Immunolocalization of Egfr protein in E18 WT (E) and Tabby (F) SMGs. In WT glands, Egf, Tgfα and Egfr proteins are localized to ductal and terminal bud epithelia. In Tabby glands, a substantial increase in immunodetectable Egf, Tgfα and Egfr proteins is seen. Bar, 20 μm.