Figure 2

Mucin protein expression in Tabby and WT glands. Mucin protein is immunolocalized in some, but not all, terminal end buds in E17 Tabby (A) and E16 WT (B) SMGs (Early Terminal Bud stage). By E18, although E18 Tabby SMGs (C) display a notable reduction in total proacini displaying mucin protein compared to E18 WT glands (D), the observation of mucin protein in all proacinar lumen in both E18 Tabby and WT glands indicates similar glandular differentiation and that both glands have achieved the Late Terminal Bud stage. Bar, 20 μm.