Rescue of ogt morphants by injection of variant 4 ogt mRNA. Lateral views of live ogt morphant injected with 50 pg β-galactosidase mRNA (A) or 50 pg ogta variant 4 mRNA (B). The image in A depicts the mild range of defects observed in morphants. (C) Graph depicting the frequency of wild type embryos in ogt morphants injected with 50 pg β-galactosidase mRNA (lane 1), 10 pg ogta variant 4 mRNA (lane 2), or 50 pg variant 4 ogt mRNA (lane 3). Injection of ogta variant 4 mRNA significantly increases the frequency of normal embryos.