Figure 1

Varicose alleles created by imprecise excision. Imprecise excision of P-element insertion line GE13049 generated an allelic series of vari. Five alleles were produced, vari^B4, vari^K4, vari^L4, vari^B5 and vari^48EP. Excision vari^48EPgenerated a protein null allele. The 3'UTR of vari overlaps with the 3'UTR of the adjacent CG9324/pomp. The vari^48EPexcision removes the 3'UTR's of both genes, and three terminal amino acids of CG9324. Start/stop codons and protein domains are colour coded as follows: start sites (green), L27N and L27C domains (pink and red. see[34]), PDZ domain (blue), SH3 domain (teal), GUK domain (orange), stop codon (purple).