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Figure 1 | BMC Developmental Biology

Figure 1

From: Transcriptional regulation of mouse alpha A-crystallin gene in a 148kb Cryaa BAC and its derivates

Figure 1

αA-crystallin protein expression during lens morphogenesis. Nuclear DAPI staining is blue and αA-crystallin immunolabeling is red. αA-crystallin is not expressed at E9.5 in the lens placode (A) but becomes visible in the lens pit at E10.5 (B). Expression intensifies in the developing lens vesicle at E11.5 (C), and is evident in the newly differentiated fiber cells at E14.5 (D), as well as within the lens epithelium. αA-crystallin expression continues in the fiber (E) and epithelial cells of the P1 lens (F). Lens epithelial cells, e; lens fiber cells, f; lens vesicle, lv; lens pit, lp. Scale bar = 100 μm.

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