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Figure 7 | BMC Developmental Biology

Figure 7

From: Expression study of cadherin7 and cadherin20 in the embryonic and adult rat central nervous system

Figure 7

Expression of cad7 in the brainstem and cerebellum in the foetus. A-J: Comparison of expression patterns of Pax6 and cad7 in the brainstem and cerebellum of the wild type (A, B, E and F) and Pax6 homozygous mutant rat (rSey2/rSey2) (C, D, G and H) on serial sagittal sections. At E20.5, Pax6 and cad7 are expressed in the pontine nucleus (PN), reticular nucleus (RT) (arrowheads in A and B) and the external germinal layer (EGL) (arrows in E and F). In the Pax6 mutant, cad7 expression is detected in the remaining RT (arrowhead in D), which is similar to Pax6 expression (arrowhead in C). The expression of Pax6 and cad7 is observed in EGL of the Pax6 mutant (arrows in G, H). I-L: Cross-sections of the E20.5 rat cerebellum. Cad7 is also expressed in the cerebellar neuroepithelium (cne) (arrows in J, bracket in L) and cerebellar deep nuclei (arrowheads in J) in contrast to the expression of Pax6 (I and K). M-N: Higher magnifications of E and F. The expression of Pax6 and cad7 is detected in both EGL (bracket) and migrating cells. URL, upper rhombic lip. Scale bars: 500 μm in A-D; 100 μm in E-H; 300 μm in I and J; 200 μm in K-M.

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