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Table 2 Classification of Gro/TLE family members and eh1 or WRPW domain containing transcription factors into the five expression domains in the developing pancreas using the GenePaint database

From: Expression of Groucho/TLE proteins during pancreas development

Symbol

GenePaint Id#o

Trunk

Tip

Epithelium

Vasculature

Mesenchyme

Not detected#

Gro/TLE family members

Tle1

MH424

    

M^

 

Tle2

MH2206

  

M

 

M

 

Tle3

MH392

  

M

 

M

 

Tle4

EB1917

     

Y

Tle5

N/A

      

Tle6

MH1997

  

S

   

Transcription factors containing an eh1 or WRPW Domain

Arx

MH740

S

     

Emx2

N/A

      

Foxa1

MH864

     

Y

Foxa2

MH515

  

M

   

Foxa3

EH531

  

M

   

Foxc1

ES2315

     

Y

Foxc2

N/A

      

Foxd3

MH620

     

Y

Hes1

N/A

      

Hes6

MH945

M

 

W

   

Hesx1

N/A

      

Hhex

EB22

  

W

   

Hlxb9

N/A

      

Msx1

N/A

      

Nkx2-2

EN1299

M

     

Nkx2-3

EB1495

    

M

 

Nkx2-5

MH1017

     

Y

Nkx6-1

N/A

      

Nkx6-2

N/A

      

Pax1

EN1275

     

Y

Pax3

ES1828

     

Y

Pou3f3

N/A

      

Pou3f4

MH930

M

     

Tbx15

EH1284

     

Y

Tbx2

EG1241

     

Y

Tbx20

EG2245

     

Y

Tcf1

EB1413

 

W

W

   

Tcf2

MH809

  

S

   

Tcf3

MH770

     

Y

Tcf4

MH934

    

M

 

Tlx1

EH430

     

Y

  1. o The accession number of the gene in the GenePaint database http://www.genepaint.org, N/A indicates that the gene is not present in the database or that the sections containing informative stain in the pancreas were not present
  2. ^ W indicates weak staining, M indicates moderate staining, and S indicates strong staining
  3. #Not detected indicates that the probe for the gene produced staining in the embryo, suggesting the probe was functional, but no staining was seen in the pancreas