Figure 2From: Msx1 and Msx2are required for endothelial-mesenchymal transformation of the atrioventricular cushions and patterning of the atrioventricular myocardiumExpression of Msx1 and Msx2 in the developing AV canal. Section in situ hybridization showed that the domains of Msx1 and Msx2 expression overlap in a subpopulation of endocardial and cushion mesenchymal cells during AV cushion morphogenesis between E9.5 and E11.5 (A-F). Msx2 also displayed strong expression in the myocardium of the AV canal and right ventricle at all developmental stages examined (B, D and F). Red asterisks indicate AV cushions. endo, endocardium; FG, foregut; IAS and IVS, interatrial and interventricular septum; LA and LV, left atrium and ventricle; myo, myocardium; RA and RV, right atrium and ventricle. Scale bars: 0.1 mm in A (for A, B), 0.2 mm in C (for C, D) and E (for E, F).Back to article page