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Figure 5 | BMC Developmental Biology

Figure 5

From: Effects of NGF, NT-3 and GDNF family members on neurite outgrowth and migration from pelvic ganglia from embryonic and newborn mice

Figure 5

Quantification of the effects of glial cell line-derived neurotrophic factor (GDNF), neurturin, artemin, NGF and NT3 on area of Tuj-1+ fibre outgrowth, from slices of embryonic day (E) 11.5 midgut (A), or embryonic day (E) 14.5 hindgut (B), cultured for 4 days. The data (mean ± SEM) show the area of immunostaining as a percentage relative to the mean immunostained area of Tuj-1+ fibres obtained from control explants at each developmental stage. Significant responses to GDNF at E11.5 (A), and neurturin at E14.5 (B) are indicated with an asterisk (one way ANOVA followed by Dunnett's post-hoc test; * – p < 0.05). "n"s refer to the number of explants analysed.

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