Figure 4From: Cloning and expression of R-Spondin1in different vertebrates suggests a conserved role in ovarian developmentGonadal expression of chicken WNT4 , assessed by in situ hybridization. A) cWNT4 is expressed in the gonads of both sexes at E4.5 (prior to sexual differentiation) (arrows). Expression is similar between the sexes at E6.5 (near the beginning of sexual differentiation), but is down-regulated in males (ZZ) by E8.5. B) Transverse sections of over-stained E8.5 whole mounts showing cWNT4 expression in the outer region of the female gonad. Weak staining in the male gonad represents background.Back to article page