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Figure 2 | BMC Developmental Biology

Figure 2

From: Control of cell cycle entry and exiting from the second mitotic wave in the Drosophiladeveloping eye

Figure 2

Dap is upregulated in Su(H) mutant clones spanning the SMW and contributes to the block of S phase entry in the SMW. (A-C) Dap protein (red) is up-regulated in Su(H) mutant cells spanning the SMW. (D-F) Dap-HB enhancer activity (red) is also upregulated in Su(H) mutant clones spanning SMW. (G-I) In dap mutant background there is a significant number of Su(H) mutant cells incorporating BrdU near SMW (red). Mutant clones are mark by absence of GFP and the arrows mark some BrdU cells in Su(H), dap double mutant clone. (J) Quantification of the number of Su(H) mutant cells incorporating BrdU in the WT (Su(H)) or dap mutant background (Su(H), dap). The average number of BrdU incorporating cells is normalized to the unit area (104 pixels) and Con 1 and Con 2 indicate the average number of BrdU incorporating cells in the SMW of WT or dap eye discs adjacent to the mutant clones.

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