TY - JOUR AU - Sukhanova, Madina J. AU - Du, Wei PY - 2008 DA - 2008/01/24 TI - Control of cell cycle entry and exiting from the second mitotic wave in the Drosophiladeveloping eye JO - BMC Developmental Biology SP - 7 VL - 8 IS - 1 AB - In the morphogenetic furrow (MF) of the Drosophila developing eye, all cells arrest in G1 and photoreceptor cell differentiation initiates. As the cells exit the MF, Notch signaling is required for the uncommitted cells to enter a synchronous round of cell division referred to as the "second mitotic wave" (SMW). How cell cycle entry and exit in SMW is regulated remains unclear. Recent studies have suggested that Notch signaling controls S phase in the SMW by regulating Cyclin A and the E2F transcription factor independent of Cyclin E. In this manuscript, we investigate the developmental regulation of cell cycle entry into and exit from SMW. SN - 1471-213X UR - https://doi.org/10.1186/1471-213X-8-7 DO - 10.1186/1471-213X-8-7 ID - Sukhanova2008 ER -