Skip to main content
Figure 6 | BMC Developmental Biology

Figure 6

From: Endothelial-specific ablation of Serum Response Factor causes hemorrhaging, yolk sac vascular failure, and embryonic lethality

Figure 6

Detection of SRF protein within vascular endothelial cells. Single-plane confocal laser photomicrographs (A-630×, B-1,000×) of ventricular tissue from wild-type E16.5 mouse heart immunolabelled with the VEC marker PECAM-1 (red) and SRF (green). (A) PECAM-1-stained cells surround vessels as well as form the epicardium (arrowheads). Cardiomyocytes within ventricular tissue show strong SRF staining (asterisks). (B) Endothelial cell-specific PECAM-1 (red; arrowheads) encircles the nuclear-localized SRF protein (green; asterisks). Scale bars: A = 40 μm; B = 4 μm.

Back to article page