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Figure 5 | BMC Developmental Biology

Figure 5

From: Pax7 is requisite for maintenance of a subpopulation of superior collicular neurons and shows a diverging expression pattern to Pax3 during superior collicular development

Figure 5

Comparative NeuN and ephrin-A2 expression profiles in the superior colliculus of Pax7 mutant and wildtype mice. NeuN expression demonstrates increased rostral expression (a) compared to caudal expression (b) at E12.5, indicating that rostral maturation precedes that of the caudal region. Figures (c) and (d) illustrate a full complement of NeuN+ cells dorsally at E15.5 and E18.5, respectively, in Pax7 mutant mice consistent with wildtype expression (data not shown). Comparison at P5 between wildtype (e) and Pax7 mutant mice (f) indicates a loss of neurons dorsally. Likewise, analysis of ephrin-A2 expression shows perturbation between wildtype (g,i) and Pax7 mutant mice (h,j) in the dorsalmost region. Scale bar: a-c,e-f 100 μm; d,i-j 200 μm; g-h 500 μm.

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BMC Developmental Biology

ISSN: 1471-213X

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