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Figure 4 | BMC Developmental Biology

Figure 4

From: Pax7 is requisite for maintenance of a subpopulation of superior collicular neurons and shows a diverging expression pattern to Pax3 during superior collicular development

Figure 4

Comparative neuronal differentiation in the developing superior colliculus of Pax7 mutant and wildtype mice at E12.5. Neuronal differentiation in the developing mouse tectum/superior colliculus of wildtype (a,c,e) and Pax7-/- mice (b,d,f) at E12.5, as indicated by βIII-tubulin (a-b),α-internexin (c-d) and doublecortin (e-f) immunostaining. Comparison shows similar neuronal differentiation, with increased spatial expression rostrally relative to caudally, with the rostral region slightly variable at different positions across the mediolateral axis, and neuronal differentiation mid-caudally restricted to the intermediate zone at the pial surface. Compare to the complementary expression of Pax3 at E12.5 (g). Scale bar: 200 μm.

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BMC Developmental Biology

ISSN: 1471-213X

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