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Figure 1 | BMC Developmental Biology

Figure 1

From: Pax7 is requisite for maintenance of a subpopulation of superior collicular neurons and shows a diverging expression pattern to Pax3 during superior collicular development

Figure 1

Pax7 expression profiles in the developing superior colliculus of Pax7 mutant and wildtype mice. Comparative Pax7 expression profiles throughout development of the mouse tectum/superior colliculus in wildtype (a,b,c,e,g,i) and Pax7+/- mice (d,f,h,j). Note expression within the intermediate zone (IZ) in both the rostral (a) and caudal (b) regions of wildtype mice at E12.5. The embryonic Pax7 profile is comparable between wildtype and Pax7+/- mice at E15.5 (c-d) and E18.5 (e-f), however at P5 there is a paucity of Pax7+ cells in the dorsalmost region of Pax7+/- mice relative to wildtype (g-h). At P18.5 Pax7 expression is similar between wildtype and Pax7+/- mice (i-j). Abbrev. IZ, intermediate zone; VZ/SVZ, ventricular zone/subventricular zone. Scale bar: a-b 100 μm, c-j 200 μm.

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BMC Developmental Biology

ISSN: 1471-213X

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