Table 3 Downregulated genes
From: Expression profiling in transgenic FVB/N embryonic stem cells overexpressing STAT3
Probe set | Identifier | RefSeq | Chr | MM/PM fold change | MM/PM p-value (t-test) | PM fold change | PM p-value (t-test) | RTQ-PCR fold change |
|---|---|---|---|---|---|---|---|---|
97283_at | developmental pluripotency-associated 3 (Dppa3) | NM_139218 | 6 | -2.16 | 0.10982 | -2.81 | 0.047749 | -11.4 ± 1.51 |
133948_at | Eukaryotic translation initiation factor 2C 4 (Eif2c4) | AI504948 | 17 | -1.53 | 0.044727 | -1.46 | 0.018363 | n.d. |
134566_at | Left-right determination factor 2 (Lefty2) | NM_177099 | 1 | -2.7 | 0.029827 | -2.32 | 0.025196 | -2.35 ± 0.23 |
103389_at | aminoadipate-semialdehyde synthase (Aass) | NM_013930 | 6 | -2.07 | 0.077262 | -1.71 | 0.100000 | n.d. |
167617_r_at | transmembrane protein 109 (Tmem 109) | NM_134142 | 19 | -1.89 | 0.036619 | -1.73 | 0.042999 | n.d. |
166131_at | enabled homolog (Enah) | NM_001083120 | 1 | -1.55 | 0.008738 | -1.46 | 0.016412 | n.d. |
138014_at | nucleoporin 153 (Nup 153) | NM_175749 | 13 | -1.55 | 0.012282 | -1.49 | 0.011324 | n.d. |
167824_f_at | S-phase kinase-associated protein 2 (p45/Skp2) | NM_013787 | 15 | -1.74 | 0.054672 | -1.62 | 0.073491 | -1.27 ± 0.03 |
100499_at | syntaxin 3 (Stx3) | NM_001025307 | 19 | -2.09 | 0.033994 | -2.03 | 0.036655 | n.d. |
166600_at | KH domain containing, RNA binding, signal transduction associated 3 (Khdrbs3) | NM_010158 | 15 | -1.66 | 0.027322 | -1.52 | 0.035974 | n.d. |
93568_i_at 93569_f_at | RIKEN cDNA 2610042L04 gene | BC096548.1 | 14 | -3.29 | 0.069938 | -2.94 | 0.070848 | n.d. |
161004_at | RIKEN cDNA 1700097N02 gene | XM_001479022 | 17 | -2.12 | 0.100000 | -2.24 | 0.002726 | n.d. |
167843_f_at | similar to RIKEN cDNA 1110051B16 gene | XM_001472554 | 14 | -2.71 | 0.004646 | -1.81 | 0.003623 | n.d. |