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Table 2 Progeny of crosses N1F/F:ZP3Cre X N1+/+ and N1F/F:ZP3Cre X N1+/lbd.

From: In vivo consequences of deleting EGF repeats 8–12 including the ligand binding domain of mouse Notch1

Female Male No. Litters Pups/Embryos Stage Genotype
  +/+ +/lbd lbd/lbd
N1F/F:ZP3Cre N1+/+ 7 42 P10 0 42 0
N1+/F:ZP3Cre N1+/+ 6 40 P10 21 19 0
N1F/F:ZP3Cre N1+/lbd 3 10 P10 0 10 0
N1F/F:ZP3Cre N1+/lbd 4 29 E9.5 0 14 15
  1. Pups at postnatal day 10 (P10) were genotyped from litters of 8 Notch1F/F:ZP3Cre or 5 Notch1+/F:ZP3Cre females mated to 6 Notch1+/+ or 2 Notch1+/lbdmales. Yolk sacs of E9.5 embryos were genotyped following timed matings of 4 Notch1F/F:ZP3Cre females to 3 Notch1+/lbdmales. N1, Notch1