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Table 2 Progeny of crosses N1F/F:ZP3Cre X N1+/+ and N1F/F:ZP3Cre X N1+/lbd.

From: In vivo consequences of deleting EGF repeats 8–12 including the ligand binding domain of mouse Notch1

Female

Male

No. Litters

Pups/Embryos

Stage

Genotype

 

+/+

+/lbd

lbd/lbd

N1F/F:ZP3Cre

N1+/+

7

42

P10

0

42

0

N1+/F:ZP3Cre

N1+/+

6

40

P10

21

19

0

N1F/F:ZP3Cre

N1+/lbd

3

10

P10

0

10

0

N1F/F:ZP3Cre

N1+/lbd

4

29

E9.5

0

14

15

  1. Pups at postnatal day 10 (P10) were genotyped from litters of 8 Notch1F/F:ZP3Cre or 5 Notch1+/F:ZP3Cre females mated to 6 Notch1+/+ or 2 Notch1+/lbdmales. Yolk sacs of E9.5 embryos were genotyped following timed matings of 4 Notch1F/F:ZP3Cre females to 3 Notch1+/lbdmales. N1, Notch1