Figure 9
From: PITX2 gain-of-function induced defects in mouse forelimb development
At E14.5 PITX2 and Six2 are fully co-expressed in non-myogenic cells. (A) H&E stained sagittal section of E14.5 Ktcn-PITX2 forelimb. The marked area is magnified in B-D. (B-D) At E14.5 Six2 expression overlaps a substantial area of the non-myogenic cells over-expressing PITX2. The marked areas are further magnified in E-F and overlaid in F'. Scale bar: 0.5 mm.