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Table 1 Genes significantly upregulated in nRBCs. Listed genes are ranked according to expression level in nRBCs shown as Log2 expression values. Genes highlighted in bold were verified by PCR.

From: Expression profiling of circulating non-red blood cells in embryonic blood

Probe Set ID

Gene Name

nRBC

RBC

Gga.1039.1.S1_at

CD61, Integrin Beta 3 (Platelet Glycoprotein IIIa)

7.53

0.81

Gga.4472.3.S1_x_at

Thymosin Beta 4 TOLL-Like Receptor 7 (TLR7)

7.5

2.35

Gga.9122.1.S1_at

ETS-1 (p54)

7.31

-0.07

Gga.15362.1.S1_at

RGS18 Regulator of G-protein Signalling 18

7.11

-3.73

Gga.1187.2.S1_s_at

PINCH-1 hypothetical

7.07

4.02

Gga.5362.1.S1_a_at

Elfin, PDZ and LIM Domain Protein 1 (PDLIM-1)

6.81

-0.18

Gga.10042.1.S1_a_at

CD200 Receptor 1 (CD200R)

6.78

-1.78

Gga.6387.1.S1_at

p21 Rac2

6.74

-1.68

Gga.2876.1.S2_a_at

VAV3

6.65

-1.71

Gga.19950.1.S1_s_at

Coagulation Factor XIII, A1 Polypeptide

6.49

-2.26

Gga.3316.1.S1_s_at

HEX probox protein

6.44

1.91

Gga.12960.1.S1_at

Phospholipase C Gamma 2 (PLCG2)

6.29

-1.81

Gga.4451.1.S1_at

Gelsolin

6.14

0.08

Gga.9413.1.A1_at

Prostaglandin-Endoperoxide Synthase 1 (COX-1)

6.06

2.28

Gga.6665.1.A1_at

Peptide Methionine Sulfoxide Reductase (MSRA)

5.98

-1.16

Gga.514.1.S1_at

Coagulation Factor X Precursor Virus Activating Protease

5.79

-1.51

Gga.7018.1.S1_s_at

Fgd3, FYVE, RhoGEF and PH domain containing 3

5.79

0.51

GgaAffx.13009.1.S1_at

Tumor Necrosis Factor Alpha Induced Protein 8 (TNFAIP-8)

5.52

1.71

Gga.4772.1.S1_at

Connexin 43 (Cx43)

5.46

-3.4

Gga.11854.1.S1_at

Tetraspanin 6 (TSPAN6)

5.44

0.48

Gga.4350.1.S2_at

FYN Oncogene Related to SRC, FGR, YES

5.32

-0.29

Gga.1193.1.S2_at

CD45, Protein Tyrosine Phosphatase Receptor Type C

5.24

-1.89

Gga.3828.1.S1_at

ZOV3, Embigin Homolog

5.24

0.61

Gga.16474.1.S1_at

Pleiotrophin (PTN) Osteoblast-Specific Factor 1 (OSF-1)

5.16

-3.79

GgaAffx.21842.1.S1_s_at

Beta Defensin 7 (Gal 7)

5.13

0.18

Gga.11496.1.S1_at

CD62L, L-Selectin

5.09

-1.48

Gga.4225.1.S1_at

Leukocyte Cell-derived Chemotaxin 2 (LECT2)

4.89

0.24

Gga.10034.1.S1_at

Similar to Plasminogen Activator Inhibitor (PAI)

4.85

-3.93

Gga.2734.1.S2_at

CD166, Activated Leukocyte Cell Adhesion Molecule (ALCAM)

4.67

-2.35

Gga.13583.1.S1_at

CD36, Thrombospondin Receptor (Platelet Glycoprotein IV)

4.66

-2.74

Gga.2967.1.S2_at

CD49F, VLA6, Integrin Alpha 6

4.47

-0.16

Gga.19342.1.S1_at

Calcium-Activated Potassium Channel Subunit Alpha, Slowpoke (Slo1)

4.45

-3.99

Gga.5758.1.S1_s_at

LYN, Yamaguchi Sarcoma Viral Related Oncogene Homolog (vYES-1)

4.45

-1.42

GgaAffx.12646.1.S1_at

Spleen Tyrosine Kinase (SYK)

4.42

-2.6

Gga.3899.3.S1_a_at

Platelet-Derived Growth Factor Alpha (PDGF-A)

4.38

-2.38

Gga.4832.1.S1_at

Interferon Inducible Transmembrane Protein 3 (IITMP3, Fragilis)

4.25

-0.06

Gga.11657.1.S1_at

Thrombin Receptor, Coagulation Factor II Receptor

4.02

-1.14

Gga.11741.1.S1_a_at

Tissue Factor Pathway Inhibitor (Lipoprotein-Associated Coagulation Inhibitor)

3.98

-2.99

Gga.15893.1.S1_at

CD49B, Integrin Alpha 2 (Platelet Glycoprotein IIb)

3.94

-2.95

GgaAffx.22186.2.S1_s_at

Interleukin-1 Receptor Accessory Protein Precursor (IL1RAP)

3.88

-1.26

GgaAffx.13138.1.S1_at

Tumor Necrosis Factor (ligand) Superfamily Member 13b (TNFSF-13b)

3.75

-1.88

GgaAffx.13210.1.S1_at

SRC Like Adaptor (SLAP)

3.62

-4.21

Gga.690.1.S1_at

LY64, MD-1

3.51

-0.47

Gga.3738.1.S1_at

B-cell Linker (BLNK)

3.46

-1.18

Gga.4943.1.S1_at

Tumor Necrosis Factor Receptor Superfamily, Member 21

3.32

-1.4

Gga.5743.1.S1_at

LY96, MD-2

3.31

-3.02

GgaAffx.20689.1.S1_at

Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene (SPI-1, PU.1)

3.29

-2.58

Gga.815.1.S1_at

CD51, Integrin Alpha V

3.02

-2.36

GgaAffx.20858.1.S1_at

Cell Adhesion Molecule with Homology to L1CAM Precursor (CHL1)

2.89

-2.24

Gga.2039.1.S1_at

Heme Oxygenase (decycling) 1 (HMOX1)

2.88

-2.69

GgaAffx.11713.1.S1_s_at

Rho Guanine Nucleotide Exchange Factor 3 (GEF-3)

2.74

-1.8

Gga.3070.1.S1_at

CD121A, Interleukin-1 Receptor Type I

2.65

-3.35

Gga.1980.1.S1_s_at

Thrombospondin 4 (THBS4)

2.59

-2.6

Gga.11824.1.S1_at

Cystatin F, Leukocystatin

2.53

-3.57

Gga.4507.1.S1_at

CD18, Integrin Beta 2

2.27

-2.61

GgaAffx.24377.2.S1_s_at

Beta Parvin

2.22

-2.93

Gga.7769.1.S1_at

Fgd5, FYVE, RhoGEF and PH Domain Containing 5

2.15

-2.87

Gga.7528.1.S1_at

Kruppel-like Factor 2 (KLF-2)

2.07

-1.91

GgaAffx.1733.2.S1_s_at

CD62P, Cell Adhesion Molecule LECAM3

1.37

-3.73