From: Abnormal skeletal and cardiac development, cardiomyopathy, muscle atrophy and cataracts in mice with a targeted disruption of the Nov (Ccn3) gene
Number of litters
Novdel3-/-
Wild type
Novdel3+/-
Embryos E12.5-E19.5
15
22
28
50
Ratio: wild type
0.8
1.0
1.8
% Loss
20
0
10
Live born >P10
7
5
11
14
0.45
1.3
55
35