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Table 1 Genotypes of Offspring from Matings of F1 and F2 Novdel3heterozygotes

From: Abnormal skeletal and cardiac development, cardiomyopathy, muscle atrophy and cataracts in mice with a targeted disruption of the Nov (Ccn3) gene

 

Number of litters

Novdel3-/-

Wild type

Novdel3+/-

Embryos E12.5-E19.5

15

22

28

50

Ratio: wild type

 

0.8

1.0

1.8

% Loss

 

20

0

10

Live born >P10

7

5

11

14

Ratio: wild type

 

0.45

1.0

1.3

% Loss

 

55

0

35