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Figure 7 | BMC Developmental Biology

Figure 7

From: Abnormal skeletal and cardiac development, cardiomyopathy, muscle atrophy and cataracts in mice with a targeted disruption of the Nov (Ccn3) gene

Figure 7

Phenotype of adult lens. A, B: Photograph of eyes of wild type (A) and Novdel3-/- (B) adult mice of six months of age, showing cataracts in both eyes in the mutant. The small white colouration in the wild type eye is an artefact due to reflected light. C-F: Haematoxylin and Eosin stained sections of wild type (C,E) and Novdel3-/- (D,F) adult eyes showing degeneration of the mutant lens, with vacuolation and loss of surface epithelium. Scale bars in E,F = 5 μm; C,D = 15 μm.

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