Aberrant epigenetic changes and gene expression in cloned cattle dying around birth

Table 4 Principal abnormalities at necropsy of dead cloned cattle^a

Cattle	Heart	Liver	Spleen	Lung	Kidney
ED1	Hypertrophy, patent foramen ovale	Hepatomegaly, congestion	Normal	Atelectasis, thickened alveolar wall	Normal
ED2	Valvular agenesis	Hepatomegaly	Hemorrhage	Atelectasis, thickened alveolar wall	Normal
ED3	Hypertrophy, hemorrhage, necrosis, thickened cardiac muscle, patent foramen ovale	Hepatomegaly, congestion	Hemorrhage, two lobes	Congestion, atelectasis, disjunct six lung lobes	Normal
LD1	Volvulus induced death, no other obvious organic pathological changes
LD2	Arthritis induces paralysis, no other obvious organic pathological changes
LD3	Intestinal spasm, no other obvious organic pathological changes

ISSN: 1471-213X