Figure 7From: Inhibition of HMG CoA reductase reveals an unexpected role for cholesterol during PGC migration in the mouseLoss of de novo cholesterol synthesis does not perturb PGC migration. E12.5 gonads from (A) a Dhcr7+/- embryo and (B) a Dhcr7-/- littermate. Gonads were stained for the PGC marker SSEA1. Similar results were seen for four Dhcr7-/- embryos derived from two litters. E12.5 gonads dissected from (C) an Sc5d +/- embryo and (D) an Sc5d-/- littermate. Similar results were seen for seven Sc5d-/- embryos derived from four litters. Scale bar is 146 μm.Back to article page