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Figure 5 | BMC Developmental Biology

Figure 5

From: Inhibition of HMG CoA reductase reveals an unexpected role for cholesterol during PGC migration in the mouse

Figure 5

Statin treatment reduces total cholesterol levels. (A) Filipin staining of control tissue. Arrow heads indicate autofluorescent cells and arrow indicates lint. (B) Filipin staining of tissue treated with 100 μM atorvastatin. (C) Average filipin staining intensity in treated and control slices normalized to control values (set to 100%). (D) Average bioprobe response in treated and control tissue normalized to controls (set to 100%). Error bars are s.e.m.. n = number of slices. " * " = groups that differed from controls (F < 0.05 Analysis of Variance from Walpole and Meyer with Fishers least significance post test). Scale bar is 100 μm.

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