Figure 1From: Inhibition of HMG CoA reductase reveals an unexpected role for cholesterol during PGC migration in the mouseThe HMGCR pathway. HMGCR is the rate-limiting enzyme that converts HMG-CoA into mevalonate. Mevalonate serves as a precursor for the synthesis of both cholesterol and isoprenoids. Enzymes inhibited in this study are indicated in red.Back to article page