Pleiotropic effects in Eya3knockout mice

Table 3 Results of behavioural observations (8–10 week old mice).

	Wild type		Eya3 ^-/-
	male	female	male	female
Parameter	n = 15	n = 9	n = 15	n = 9
Forward locomotor activity (total distance travelled) [cm]	3387.2 ± 124.9	3534.3 ± 115.5	3086.8 ± 126.5*	3248.6 ± 71.4*
Speed of movement (maximum velocity) [cm/sec]	62.9 ± 1.9	59.8 ± 3.2	55.0 ± 1.9*	58.2 ± 1.9*
Turns [frequency]	1714.9 ± 46.1	1776.8 ± 41.7	1610.3 ± 41.6*	1688.8 ± 39.8*
Exploratory behaviour (hole exploration) [latency]	14.6 ± 3.7	13.9 ± 3.1	8.1 ± 1.5*	8.5 ± 1.6*
Grip strength (force) [p]	121.7 ± 2.8	99.3 ± 3.7	102.8 ± 4,9**	89.9 ± 3.9**

*p < 0.05; **p < 0.01 (as compared to the corresponding group of wild-type mice); data are presented as mean ± standard error of the mean

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