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Table 2 ECG-Parameters (15 week old mice)

From: Pleiotropic effects in Eya3knockout mice

 

Wild type

Eya3 -/-

 

male

female

male

female

Parameter

n = 8

n = 9

n = 10

n = 9

PQ interval [ms]

38.6 ± 0.7

40.8 ± 0.7

41.3 ± 1.6*

43.6 ± 0.9*

P-wave duration [ms]

20.4 ± 0.6

20.4 ± 0.8

20.8 ± 0.6

21.4 ± 0.3

QRS-complex duration [ms]

9.6 ± 0.2

9.6 ± 0.2

10.0 ± 0.2

9.8 ± 0.3

QT interval [ms]

46.2 ± 1.3

41.7 ± 0.6

45.6 ± 2.1

42.7 ± 0.6

QTcorrected [ms]

40.6 ± 1.4

36.5 ± 0.5

40.1 ± 1.5

38.2 ± 0.7

RR interval [ms]

130.6 ± 3.8

130.9 ± 4.1

130.1 ± 4.9

125.2 ± 3.7

Heart rate [bpm]

463.7 ± 13.5

463.4 ± 14.2

469.1 ± 18.6

482.7 ± 13.3

JT interval [ms]

4.1 ± 0.6

3.7 ± 0.1

6.0 ± 1.1*

5.4 ± 0.4*

ST interval [ms]

36.6 ± 1.5

32.1 ± 0.6

35.6 ± 2.1

32.9 ± 0.6

Q amplitude [mV]

0.01 ± 0.00

0.02 ± 0.01

0.04 ± 0.01**

0.03 ± 0.01**

R amplitude [mV]

3.10 ± 0.18

3.16 ± 0.35

2.32 ± 0.14**

2.33 ± 0.29**

S amplitude [mV]

-1.26 ± 0.22

-1.03 ± 0.16

-0.95 ± 0.14

-1.01 ± 0.16

QRS amplitude [mV]

4.35 ± 0.17

4.19 ± 0.40

3.28 ± 0.13***

3.34 ± 0.22***

  1. *p < 0.05; **p < 0.01; ***p < 0.001 (as compared to the corresponding group of wild-type mice); data are presented as mean ± standard error of the mean
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BMC Developmental Biology

ISSN: 1471-213X

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