Figure 8
From: Domain-specific regulation of foxP2 CNS expression by lef1
Model of foxP2 regulation in the CNS. In the telencephalon, an unknown factor X activates foxP2 expression. In the tectum (and MHB) Lef1 directly binds to enhancer elements of foxP2, leading to foxP2 expression. In the hindbrain expression of foxP2 is Lef1-dependent, but indirectly, since Lef1 is not expressed in the hindbrain.