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Table 1 Genes showing decreasing expression in longissimus muscle of bovine fetuses over developmental time1

From: Gene expression studies of developing bovine longissimusmuscle from two different beef cattle breeds

Gene2 GenBank Accession3 Number of array elements4 Gene expression ratio5 135 d/60 d Gene expression ratio5 195 d/60 d Gene expression ratio5 birth/60 d
cadherin 11, type 2, OB-cadherin (osteoblast) (CDH11) DW521798 1 0.26** 0.23** 0.10**
collagen, type I, alpha 1 (COL1A1) CF613531 14 0.87 0.74 0.16**
collagen, type I, alpha 2 (COL1A2) CF613950 9 0.75 0.64** 0.15**
collagen, type III, alpha 1 (COL3A1) CF613798 29 0.72 0.78 0.15**
collagen, type XII, alpha 1 (COL12A1) CF614200 1 0.48** 0.23** 0.12**
collagen, type XV, alpha 1(COL15A1) DW521810 1 0.58** 0.41** 0.18**
fibrillin 1 (FBN1) CF765332 4 0.57** 0.60** 0.23**
fibronectin 1 (FN1) CF614211 7 0.39** 0.36** 0.08**
follistatin-like 1 (FSTL1) CF613847 1 0.61** 0.35** 0.13**
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 (GNAI1) DW521797 1 0.58** 0.50** 0.20**
glypican 3 (GPC3) DW521793 1 0.91 0.84 0.11**
Insulin-like growth factor binding protein 5 (IGFBP5) CF614176 1 0.71 0.72 0.21**
lumican (LUM) CF613654 2 0.79 0.64** 0.16**
osteoglycin (OGN) CF614268 1 0.59** 0.67* 0.19**
plastin 3 (T isoform) (PLS3) DW521782 1 0.49** 0.43** 0.20**
osteonectin (SPARC) CF613734 8 0.69* 0.68* 0.21**
osteopontin (SPP1) DW521777 3 0.53** 0.19** 0.15**
stathmin 1/oncoprotein 18 (STMN1) DW521774 1 0.54** 0.38** 0.10**
tubulin, alpha 1 (TUBA1) CF613655 2 0.54** 0.46** 0.17**
vimentin (VIM) CF613639 7 0.51** 0.49** 0.16**
  1. 1* indicates a statistically significant decrease in gene expression at P < 0.05 level; ** indicates a statistically significant decrease in gene expression at P < 0.01 level.
  2. 2Sequence annotation was carried out using approved gene symbols (human genome nomenclature) via the IBISS4 database [17]. BLAST [15] scores > 110 and e-values < 2 E-23 were accepted for annotation purposes.
  3. 3in cases where more than 1 microarray element was used to calculate the expression data, the accession number of 1 representative element is shown.
  4. 4Number of microarray elements representing the same gene that were used to calculate the expression data.
  5. 5To obtain the ratios shown, averaged absolute microarray signal intensity values for d 135, 195 and birth were divided by the signal intensities measured at d 60.