Skip to main content

Table 2 Knockdown GSK3β levels that disrupt normal cardiac jogging and looping

From: Glycogen synthase kinase 3α and 3β have distinct functions during cardiogenesis of zebrafish embryo

  No. of embryos Left-jog No-jog Right-jog No. of embryos D-loop No-loop L-loop
Uninjected 72 93% 2.8% 4.2% 132 92.5% 3% 4.5%
2 ng gsk3α -MO 63 87.3% 7.9% 4.8% 74 93.2% 4.1% 2.7%
1 ng gsk3α -MO 58 93.1% 5.2% 1.7% 90 94.5% 2.2% 3.3%
6 ng gsk3β -MO 93 17.2% 69.9% 12.95 159 40.3% 45.3% 14.4%
4 ng gsk3β -MO 86 22.1% 67.4% 10.5% 101 40.6% 44.6% 14.8%
2 ng gsk3β -MO 62 45% 50% 5% 107 70.1% 22.4% 7.5%
  1. gsk3α morphants were analyzed for heart positioning at 36 to 48 hpf; gsk3β morphants were analyzed for heart positioning at 24 to 36 hpf.