Figure 4
From: Wnt signaling induces differentiation of progenitor cells in organotypic keratinocyte cultures
Wnt-expressing keratinocytes are progressively excluded from the basal replicative layer. Samples described in the legend to Fig. 2 were stained for lacZ expression to illustrate the distribution of Wnt1- (or control) expressing cells. Panel B) shows the proportion of cells that expressed lacZ for each cell strain at plating. The exclusion of lacZ-positive basal cells was quantified over time (C).